Season
- Season 22 2014-09-02
- Season 21 2014-01-06
- Season 20 2013-01-02
- Season 19 2012-01-03
- Season 18 2011-01-03
- Season 17 2009-08-31
- Season 16 2008-09-02
- Season 15 2007-09-04
- Season 14 2006-08-28
- Season 13 2005-08-29
- Season 12 2004-08-23
- Season 11 2003-09-01
- Season 10 2002-09-03
- Season 9 2001-08-20
- Season 8 2000-08-21
- Season 7 1999-09-07
- Season 6 1998-08-31
- Season 5 1997-09-01
- Season 4 1996-09-02
- Season 3 1995-09-04
- Season 2 1994-08-29
- Season 1 1993-08-30
Episode
- Episode 1: Lena Dunham; Max Greenfield; Brandy Clark
- Episode 2: Joel McHale; Marv Albert; Washed Out
- Episode 3: Scarlett Johansson; John Grant
- Episode 4: Anderson Cooper; Bobby Moynihan; Will Hoge
- Episode 5: Mindy Kaling; Jeff Altman; Red Fang
- Episode 6: Bill Cosby; Sleigh Bells
- Episode 7: Michael Strahan; Jennifer Nettles
- Episode 8: Kevin Hart; Mo Rocca; The Orwells
- Episode 9: Brian Williams; Rosanne Cash
- Episode 10: Don Cheadle; Myq Kaplan; Roadkill Ghost Choir
- Episode 11: Andy Samberg; Michael B. Jordan; Ellie Goulding
- Episode 12: Martin Scorsese; Allison Williams; Cults
- Episode 13: Rachel Maddow; Spike Jonze; No Age
- Episode 14: Kevin Bacon; Pat McGann; Devon Avenue
- Episode 15: Louis C.K.; B.J. Ganem; Artic Monkeys
- Episode 16: Eric Stonestreet; Nick Goepper; Bastille
- Episode 17: Drew Brees; B.J. Novak; Against Me!
- Episode 18: Dr. Phil McGraw; Danny Koker; Dum Dum Girls
- Episode 19: Bill Murray; Eagulls
- Episode 20: Will Arnett; Broken Bells
- Episode 21: George Clooney; Sting
- Episode 22: Matt Damon; Lenny Kravitz
- Episode 23: Patrick Stewart; The Flaming Lips
- Episode 24: Regis Philbin; Ms. Lauryn Hill
- Episode 25: Kevin Spacey, Amber Heard, a Top Ten List presented by the cast of
- Episode 26: Sage Kotsenburg, Kate Mara
- Episode 27: Kaitlyn Farrington, Lupita Nyong'o, Little Dragon
- Episode 28: Keri Russell, Terry Fator
- Episode 29: Pauley Perrette, Jeff Caldwell, Lake Street Dive
- Episode 30: Kaley Cuoco-Sweeting, Dale Earnhardt, Jr., The Fray
- Episode 31: Olympic Gold Medalist Ted Ligety, Kat Dennings, Lo-Fang
- Episode 32: Meredith Vieira, Band of Horses
- Episode 33: Stupid Human Tricks, Simon Helberg, Young the Giant
- Episode 34: Jack (Jungle) Hanna, Jake Johannsen
- Episode 35: Zach Braff, Sgt. Brendan Marrocco & Dr. Andrew Lee, Future Islands
- Episode 36: Michael Keaton, Phantogram
- Episode 37: Tom Selleck, Carrie Brownstein, David Nail
- Episode 38: Tom Brokaw, Andrew Hadlock, Bob Mould
- Episode 39: Mary-Louise Parker, Lenny Marcus, Joan Jett & the Blackhearts
- Episode 40: Sen. John McCain, Little Mix
- Episode 41: Jason Bateman, Miles Teller, Gary Allan
- Episode 42: Sylvester Stallone, Theo James, Ledisi
- Episode 43: Bryan Cranston, Melissa Rauch, Le1f
- Episode 44: Bill O'Reilly, Nick Griffin, the Dough Rollers
- Episode 45: Jimmy Carter
- Episode 46: Emma Watson, Nick Offerman, a musical tribute to Johnny Cash
- Episode 47: Peter Dinklage, Hari Kondabolu, Sage the Gemini
- Episode 48: Cobie Smulders, Nick Cannon, Manchester Orchestra
- Episode 49: Kristin Chenoweth, Amy Schumer, Johnnyswim
- Episode 50: Bill Murray, Martha Stewart, Lady Gaga
- Episode 51: Johnny Depp, Kevin Drew
- Episode 52: Billy Crystal, Tony Hale, Liv Warfield
- Episode 53: Rob Lowe, Brooklyn Decker, London Grammar
- Episode 54: Lindsay Lohan, Jamie Edwards, Real Estate
- Episode 55: Courteney Cox, Jimmie 'J.J.' Walker, Christina Perri
- Episode 56: Stephen Colbert, Robin Roberts, Kelis
- Episode 57: Sally Field, Timothy Simons, Needtobreathe
- Episode 58: Neil Patrick Harris, Sarah Hyland, Ray LaMontagne
- Episode 59: Piedmont Bird Callers, Michael J. Fox, Naughty Boy
- Episode 60: Joel McHale, Vera Farmiga, Aloe Blacc
- Episode 61: Lucy Liu, Ziggy Marley
- Episode 62: Kiefer Sutherland, Adam Resnick, Benjamin Booker
- Episode 63: Louis C.K., a performance from the Broadway cast of Rocky
- Episode 64: Don Rickles, Carmen Lynch, the Ghost of a Saber Tooth Tiger
- Episode 65: Shailene Woodley, Peyton Manning
- Episode 66: Jon Cryer, Elizabeth Olsen, Foster the People
- Episode 67: Mariah Carey, Rick Harrison
- Episode 68: James Franco, Idina Menzel, a performance by the Broadway cast of 'If/Then'
- Episode 69: Nathan Fillion, Tom Dreesen, Hunter Hayes
- Episode 70: Harry Connick Jr., Jesse Eisenberg, the Black Keys
- Episode 71: Jim Parsons, Julie Chen, Hozier
- Episode 72: Barbara Walters, Elle Fanning, Randy Houser
- Episode 73: Adam Sandler, Thomas Haden Church
- Episode 74: Lea Michele, Andy Kindler, Chromeo
- Episode 75: Jack Hanna, Stephen Malkmus & the Jicks
- Episode 76: Kid scientists, Sarah Silverman, We Are Scientists
- Episode 77: Sgt. Kyle J. White, Judy Greer, Dierks Bentley
- Episode 78: Donald Trump, Indianapolis 500 winner Ryan Hunter-Reay, Elizabeth Cook
- Episode 79: Martin Short, John Oliver, Spanish Gold
- Episode 80: Anderson Cooper, Victor Espinoza, the Afghan Whigs
- Episode 81: Hugh Jackman, Joe List, Elvis Costello
- Episode 82: Kelsey Grammer, Willie Nelson
- Episode 83: Dave Chappelle, Laura Prepon, a Top Ten List presented by Miss USA, the Orwells
- Episode 84: Christopher Walken, Janelle Monae, Tatiana Maslany, Miss USA 2014
- Episode 85: Regis Philbin, Paul Morrissey, First Aid Kit
- Episode 86: Susan Sarandon, Whitney Cummings, Angel Olsen, David Sanborn
- Episode 87: Olivia Wilde, Shep Gordon, Empires
- Episode 88: Dana Carvey, Ellie Kemper, Sam Smith
- Episode 89: Paul Rudd, Jeff Altman, John Doe
- Episode 90: Adam Levine, Gen. Frank J. Grass, Broken Bells
- Episode 91: Melissa McCarthy, Rachelle Lefevre, Phish
- Episode 92: Mark Wahlberg, Ben Falcone, Hurray for the Riff Raff
- Episode 93: Mark Ruffalo, Former Marine Lance Cpl. William 'Kyle' Carpenter
- Episode 94: Halle Berry, Steve Young, War on Drugs
- Episode 95: Joan Rivers, Capital Cities
- Episode 96: Lizzy Caplan, Sleeper Agent
- Episode 97: Michael Douglas, Paul Morrissey, Kiesza
- Episode 98: Kurt Russell, Hannibal Buress, Sturgill Simpson
- Episode 99: Jason Segel, Liv Tyler, Trampled By Turtles
- Episode 100: Emma Stone, Nathan Fielder, American Authors
- Episode 101: Colin Firth, Tommy Johnagin, EMA
- Episode 102: Jeff Daniels, Norah O'Donnell, A Special Performance of 'MacArthur Park'
- Episode 103: Ricky Gervais, Taylor Schilling, Eli Young Band
- Episode 104: Eric Stonestreet, Brody Dalle
- Episode 105: Staff Sgt. Ryan Pitts, Sharon Van Etten
- Episode 106: John C. Reilly, Rachelle Lefevre, Conor Oberst
- Episode 107: Chris Pratt, Rodrigo y Gabriela
- Episode 108: Zoe Saldana, Crash
- Episode 109: Julia Louis-Dreyfus, Simon Amstell, David Gray
- Episode 110: Bruce Willis, the Gaslight Anthem
- Episode 111: Joseph Gordon-Levitt, Novak Djokovic, Robby Johnson
- Episode 112: Kathy Griffin, Ken Burns, Jeremy Messersmith
- Episode 113: Serena Williams, Chadwick Boseman, Echo & the Bunnymen
- Episode 114: Michael Cera, dock diving dogs, Lyle Lovett
- Episode 115: Howie Mandel, EMA
- Episode 116: James McAvoy, Chris Russo, The Last Internationale
- Episode 117: Mike Myers, Bonnie McFarlane, John Fullbright
- Episode 118: Luke Wilson, Julie Chen, Lee Brice
Late Show with David Letterman Season 21 Bill Cosby; Sleigh Bells
David Letterman uses mature humor to appeal to his audience in this weeknight series, which gets its music from a house band led by Paul Shaffer. Among the show's most-famous segments are the Top Ten List and Stupid Pet Tricks, the latter of which subsequently led to an additional recurring segment called Stupid Human Tricks.
